Monday, February 16, 2009

Biocidal and antifertility activities of organotitanium and organozirconiumcomplexes derived from nitrogen and sulphur/oxygen donor ligands

Biocidal and antifertility activities of organotitanium and organozirconium complexes derived from nitrogen and sulphur/oxygen donor ligands Saurabh Dave, Ashu Chaudhary, Mithlesh Agawal, S C Joshi & R V Singh*

A new class of unsymmetrical organotitanium(IV) and organozirconium(IV) complexes of biologically potent ligands derived from heterocyclic ketones and semicarbazide hydrochloride/ thiosemicarbazide have been prepared and characterized on the basis of IR and 1H NMR spectral studies and elemental analysis, conductance measurement and molecular weight determinations. The ligands act as monobasic bidentate with N OH and N SH as donor systems. All the organotitanium(IV) and organozirconium(IV) complexes and their parent ligands have been screened against a number of microbes and their sterilizing power on male rat has been tested and discussed with positive findings.



Indian Journal of Chemistry
Vol. 42A, February 2003, pp 275-279

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